The SIDP Podcast
2 months ago

#96 – The Tortured Stewards & Surgeons Department

Episode Notes

The Society of Infectious Diseases Pharmacists is excited to invite you to the first ever meeting (via Breakpoints) of The Tortured Stewards & Surgeons Department. Today’s agenda items: optimal management of perioperative antibiotics and prevention of surgical site infections.

Drs. Trisha Peel (@DrTrishaPeel), Michael Calderwood (@CalderwoodMD) and Patch Dellinger join Dr. Jillian Hayes (@thejillianhayes) to discuss some of the controversies we encounter while managing antibiotics in the perioperative space. Does anyone really need post-op antimicrobial prophylaxis longer than 24 hours? Where should vancomycin be fitting into surgical prophylaxis regimens? Can we truly give pre-operative cefazolin to patients with a penicillin allergy? Tune in for the answers to these questions and more!

Learn more about the Society of Infectious Diseases Pharmacists: X: @SIDPharm ( Instagram: @SIDPharm ( Facebook: LinkedIn:

If you’d like more information about the CALIPSO trial, please visit this link:


  1. SSI Infection Prevention Review:,use%20a%20chlorhexidine%20gluconate%2Dalcoho
  2. Strategies to prevent surgical site infections in acute-care hospitals: 2022 Update:
  3. American College of Surgeons and Surgical Infection Society: Surgical Site Infection Guidelines, 2016 Update: 
  4. 2017 CDC Guidelines: 
  5. 2018 WHO Guidelines: 
  6. ASHP Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery: 
  7. Surgeons as Stewards: 
  8. Li et al, Arthroplasty 2022: 
  9. Dutch Arthroplasty Register Study: 
  10. de Jonge Meta-Analysis on duration and incidence of SSI: 
  11. Prolonged Antibiotic Prophylaxis After Cardiovascular Surgery and Its Effect on Surgical Site Infections and Antimicrobial Resistance:
  12. RCT - Nasal Iodophor Antiseptic vs Nasal Mupirocin Antibiotic in the Setting of Chlorhexidine Bathing to Prevent Infections in Adult ICUs: 
  13. NYU Langone Study - Preventing Surgical Site Infections: A Randomized, Open-Label Trial of Nasal Mupirocin Ointment and Nasal Povidone-Iodine Solution: 
  14. Trial of Vancomycin and Cefazolin as Surgical Prophylaxis in Arthroplasty:
  15. What Is the Primary Driver of Preoperative Vancomycin Use? It’s Not Methicillin-resistant Staphylococcus aureus—or Allergy: 
  16. Drug allergy: a 2022 practice parameter update: 
  17. Perioperative use of cefazolin without preliminary skin testing in patients with reported penicillin allergy: 
  18. Timing of Surgical Prophylaxis RCT: 
  19. Propensity Score-Weighted Analysis of Postoperative Infection in Patients With and Without Preoperative Urine Culture: